Brain Boosting Bacopa Monnieri – What Science Says About Bacopa

Bacopa monnieri is traditional Ayurvedic medicinal herb grown in India. It has been widely touted as a brain booster with other positive effects such as reduction of anxiety. Often called water hyssop, it is a popular plant used in aquariums.

The herb contains many active components including alkaloids and saponins (that form a soapy froth when shaken in a water solution). Most people recognize the saponins Bacosides A and B as the most significant components.

Bacopa monnieri is marketed by many supplement manufacturers which use a variety of phrases to describe its effects. Some of these marketing slogans include:

  • Optimize your brain power
  • Supports memory enhancement & learning
  • Supports memory, enhances mental performance
  • Brain & memory support
  • Mental focus
  • Support cognitive function and brain health
  • Mental alertness
  • Excellent rejuvenative for the mind
  • Benefits congnitive functions

These claims make it seem like you should start taking bacopa monnieri before your next algebra test or your final exams to make sure you get a high grade. After all, you want every advantage possible to succeed in life.

But, what do the scientific studies show about the benefits of bacopa monnieri? Are these marketing slogans simply hype that over-promise what you can really expect?

Scientific Studies of Bacopa Monnieri

Human scientific studies of bacopa monnieri almost always provide subjects with enough capsules to last 12 weeks. It seems to take 12 weeks, 3 months, for bacopa to show an effect. Some studies last longer to see the residual effects.

The dose used is normally that recommended by the Central Drug Research Institute (CDRI), a premier drug research institute of India. This dose is often 300 mg for persons under 90 kg (190 pounds), and 450 mg for persons over 90 kg. This is equivalent to 6g and 9g of dried rhizome.

Most double-blind placebo-controlled studies work with 50 to 100 test subjects. These studies are not conducted by large pharmaceutical manufactures who can afford to run trials with thousands of subjects. This herb is not going to generate billions of dollars of profit for the pharmaceutical industry.

The chronic effects of an extract of Bacopa monniera (Brahmi) on cognitive function in healthy human subjects is a study that was reported in the journal Psychopharmacology.

Forty-six healthy volunteers (11 males and 35 females) were recruited for the study. There were randomly dividied into two groups, one taking B. monniera (300 mg) daily and the other group taking an identical looking placebo.

All members of the trial underwent an initial 30 minute test of memory skills. They were then given the bottles of capsules there were to take for 12 weeks. The subjects were tested again after 5 weeks and after 12 weeks.

These tests were standard tests of “attention, short-term memory, verbal learning, memory consolidation, executive processes, planning and problem solving, information processing speed, motor responsiveness, and decision making.”

There were no significant differences between the groups after 5 weeks. But, after 122 weeks, the group taking bacopa monnieri showed significant positive effects in the follow areas:

  • Improved speed of visual information processing
  • Learning rate
  • Memory consolidation
  • Decrease in forgetting rate
  • Decrease in anxiety

The reseachers concluded that “the current finding suggests that B. monniera may improve higher order cognitive processes that are critically dependent on the input of information from our environment such as learning and memory.”

Another study was reported in the article Chronic Effects of Brahmi (Bacopa monnieri) on Human Memory which was published in the journal Neuropsychopharmacology.

This study was a double-blind, randomized, placebo controlled study. The study began with 84 healthy volunteers, of which 76 adults, 28 males and 48 females, between 40 and 65 years of age completed the study. These volunteers were tested for an hour on various memory functions prior to the trial, after the 3 month trial, and again 6 weeks later.

At the end of the 3 month trial period the Bacopa group showed significantly better performance on delayed recall of word pairs over the placebo group. The testing 6 weeks after the trial showed no significant differences between the groups.

The reseachers conclude that “the effect appears to be a reduction in the amount of information lost from memory.”

Another study investigated the Effects of a Standardized Bacopa monnieri Extract on Cognitive Performance, Anxiety, and Depression in the Elderly: A Randomized, Double-Blind, Placebo-Controlled Trial and was published in the Journal of Alternative and Complementary Medicine.

This two-group randomized, placebo-controlled, double-blind trial study recruited 54 participants aged 65 and older who lived independently with no signs of dementia. Forty-eight volunteers completed the study, with 24 participants in the Bacopa and plecabo groups. The Bacopa group took 300 mg per day of B. monnieri extract while the placebo group took a similar looking capsule. The Bacopa tablet contained the equivalent of about 15 g of herb and 150 mg of the bascosides A nad B.

The primary interest was in delayed recall of verbal information. Other tests were also included such as the Stroop task of recognized incongruous stimuli (such as recognizing the word green when it is printed in red).

The intervention (trial) involved 12 weeks of taking the B. monnieri or placebo.

The group taking Bacopa showed significantly improvement in the memory recall task and shortened reaction times in the Stroop test compared to the placebo group. In addition, the Bacopa group showed a decrease in depression and anxiety compared to the placebo group.

The researchers concluded that “this study provides further evidence that standardized extracts of B. monnieri have potential for safely enhancing cognitive performance in aging.”

Conclusions

Bacopa Monnieri: Amazing And Proven Herb For Memory

In this video Dr Meschino explains how bacopa monnieri is proven to improve memory in various types of memory-challenged patient studies. For more information from Dr Meschino Click Here.

Research studies show bacopa monnieri has positive effects on short term memory retention. Other benefits include recognizing information when presented in new or novel ways (incongruous information) and reduces depression and anxiety. These effects typically take 12 weeks to become apparent.

With our current aging population wanting to clear up “fogginess” as well as young people looking to have a sharper mind, boosting brain function is a highly desired goal. The excelling reviews for Brain Boost have shown that this multi-ingredient product has positive effects for many people.

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Do You Have a Magnesium Deficiency?

Magnesium plays important roles in the body. It is needed for enzyme activity by over 300 different biological processes. All enzymes associated with ATP require Magnesium. And, you may know that adenosine triphosphate (ATP) provides energy to all cells.

Depending on just how much magnesium in the blood is considered normal, anywhere from 4.8% to 47% of all patients in hospitals are deficient in magnesium. Up to 65% of patients in intensive care are deficient, and low levels of Magnesium are associated with a higher mortality rate.

How Much Magnesium is Required?

The daily dietary allowance for magnesium set by the National Academy of Science and the Institute of Medicine is 6 mg per kg of body mass. On average, this means about 400-420 mg per day for men and 310-320 mg per day for women.

It is estimated that between 50% and 85% of those living in the United States fail to reach these levels of magnesium intake. A major reason for this is the high consumption of refined and processed foods that are deficient in magnesium. One study, for example, showed that refining and processing wheat to white flour, rice to polished rice, and corn to starch removes from 82% to 97% of the magnesium.

What Are the Symptoms of Magnesium Deficiency?

Because magnesium is used in all energy producing systems as well as other systems, the symptoms of magnesium deficiency are widespread an varied. Here are some conditions to look for:

  • Hypertension
  • Insomnia
  • Generalized weakness
  • Apathy
  • Depression
  • Muscle cramps
  • Nervousness
  • Arteriosclerotic vascular disease
  • Atrial or ventricular arrhythmias
  • Atrial tachycardia
  • Atrial fibrillation
  • Exercise-induced chest pain
  • Osteoporosis
  • Neuromuscular irritability
  • Tremor
  • Convulsions
  • Anorexia
  • Delirium
  • Hallucinations
  • Psychosis
  • Vomiting
  • Sudden death

Magnesium Deficiency: 8 Warning Signs

According to Norman Shealy, MD, Ph.D, an American neurosurgeon and a pioneer in pain medicine, “Every known illness is associated with a magnesium deficiency and it’s the missing cure to many diseases.” Not only does magnesium help regulate calcium, potassium and sodium, but it’s essential for cellular health and a critical component of over 300 biochemical functions in the body.

Even glutathione, your body’s most powerful antioxidant that has even been called “the master antioxidant,” requires magnesium for its synthesis. Unfortunately, most people are not aware of this, and millions suffer daily from magnesium deficiency without even knowing it.

A major problem with many of these milder symptoms is that people often think that their condition is “normal.” They do not ask their doctor to test their magnesium levels so they do not take corrective action.

What Foods Contain Magnesium?

A hundred years ago, most people drank was just as it came from a water well. Water from a well contains minerals from the soil that our bodies absorbed. Today we call this “hard” water. Now we typically remove these minerals from our water, or use a water “softener” to get more pure water. So, we have to look to food sources for our minerals, including magnesium.

Magnesium is plentiful in natural foods. Some good source of magnesium include:

  • Dark leafy green vegetables (as a component of chlorophyll)
  • Coca derivatives, especially dark chocolate
  • Nuts (almonds, pecans, cashews, Brazil nuts) and seeds
  • Whole grains (like wheat with its bran and germ)
  • Legumes
  • Soy products like soy flour and tofu
  • Seafoods (fatty fish like salmon, mackerel and halibut)
  • Meats

Of course, these sources of magnesium need to be grown and cultivated from soils that have sufficient magnesium so the plants can draw magnesium into their cells. The website Ag Professional shows the concentrations of magnesium in Kansas soils ranges from 38 centimoles per kg of soil down to 4 centimoles per kg. Since Kansas grows a great deal of wheat, corn, soybeans, grain sorghum, and hay, both people and animals consuming their produce may not be getting the expected amount of magnesium.

This is of particular concern where farmers may only fertilize their crops with nitrogen, phosphorus, and potassium (NPK). These elements make the plants grow strong roots with tall and strong stalks, and plentiful produce. But, on low magnesium soils, the farmer should add magnesium to the soil (with products such as dolomitic limestone, Epsom salts, potassium magnesium sulfate).

Unfortunately, we don’t know the condition of the soil used to grow food products we buy in the store.

How We Deplete Our Bodies of Magnesium

Magnesium is absorbed into the blood stream along the entire intestinal tract. Ionic magnesium is most efficiently absorbed in the small intestine.

But some substances can bind to the magnesium ion, preventing it from being absorbed. High dietary fiber, phytate foods (like bran and seeds), high oxalate foods (like Spinach bran and rhubarb), and high phosphate foods (like dairy, fish and meat) can reduce the absorption of magnesium.

Your kidneys are the primary exit point for magnesium. The kidneys control the blood magnesium level within a narrow range. Kidneys can remove excess magnesium and conserve magnesium when you are depleted. Diuretic drugs that increase urine flow can prevent re-absorption in the kidneys and cause unwanted magnesium loss. Lipid-lowering drugs also cause excess magnesium loss.

Also, alcohol, caffeine and sugar accelerate magnesium loss. Within minutes of consuming alcohol magnesium excretion can increase above normal by as much as 260%.

Organic Source of Magnesium and Other Minerals

Whole leaf wheat grass powder when grown, processed and stored under optimal conditions is considered one of the most potent leafy green vegetables available. Consider organic wheat grass as a source of your daily magnesium.

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References for Further Reading

Pollution and Weight Loss

Pollution is a fact of life in an industrialized society. Pollution, by its very definition, can cause harm to people, animals, and plants. As far as humans are concerned, pollution contributes to a number of serious illnesses including obesity and increased mortality.

Pollutants in the Atmosphere

A major pollutant produced by combustion is NO, nitrogen oxide. This reacts with ozone to for NO2. Another pollutant is SO2 which is produced by burning sulphur-containing fossil fuels (primarily coal and heavy oils).

Volatile organic compounds (VOCs) are another class of atmospheric pollutants. These includes numberous chemicals or an organic nature such as benzene.

Most atmospheric pollutants affect the respiratory system, but some can get into the blood and cause other diseases such as cancer.

Organic Pollutants

These chemicals last a long time in the environment and move though the food chain. These include pesticides, dioxins, and PCBs. Dioxins are formed by incomplete combustion and whenever plastics are burned. While dioxins are not dissolved by water, they enter the food chains by binding to lipids or fats.

Heavy Metals

The include arsenic, cadmium, chromium, copper, lead, manganese, mercury, nickel, silver, vanadium, and zinc. While these heavy metals are required for bodily functions, they should be present in the body only as “trace” elements. When ingested at higher concentrations than they are eliminated, they can reach dangerous levels and adversely affect health.

Heavy metals like lead, mercury, and arsenic as well as dioxins play an important part in kidney disorders, memory disorders, sleep disorders, fatigue, tremors, blurred vision, speech disorders, and other neurological impairments.

Particulate Matter

The air we breathe in composed mainly of nitrogen, oxygen, argon, and carbon dioxide. A few other trace gases are present as well as water vapor.

pollution photo

Photo by aguscr

In addition to these components of air, there are various other particles carried by the air like dust and particulates created by volcanoes or fires. But, many types of particles are created from deliberate human sources like factories, power plants, incinerators, vehicles, and construction activities.

The sizes of the particles determine where their effects will be felt. Larger particles will affect the upper respiratory tract while finder particles will be deposited in the lungs. Most people believe that the finer particles are more injurious to human health.

Studies with mice have found that exposure to airborne pollutants causes weight gain. Human studies also confirm exposure to particulate matter in the air promotes weight gain. One human study found that the level of prenatal exposure to polycyclic aromatic hydrocarbons was a significant prredictor of childhood obesity at 5 and 7 years of age.

Another study examined the effect of traffic pollution on children. They recruited participants in 45 schools in 13 communities of southern California. The weight and height of 4,550 children were measured annually. The researchers began with those children in kindergarten or 1st grade and continued for the next 4 years. The researchers found those children living with the highest levels of pollution had a 13.6% greater increase in annual BMI growth compared to those children living in the lowest traffic pollution areas.

How to Detox Your Body

Pollution causes irritation, inflammation, and increases insulin resistance. It can cause weight gain and definitely interferes with your attempts at weight loss.

Since pollution is a fact of life, we should be concerned about removing as much toxicity from our bodies as possible. This is where healthy eating comes in.

Nutrients that have natural chelation properties are especially important. These include antioxidants, herbs, minerals, essential amino acids, and fiber. Glutathione, vitamins C, E, and A are helpful. Polyphenols in most plants help prevent and protect cells from oxidative stress.

Red Tea Detox Allows You to Lose Weight

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References for your own research:

Stem Cell Therapy Can Help You

Stem cells from your own body’s fat cells can be extracted, concentrated and reintroduced into your body. They help your body heal joint arthritis, repair heart damage, restore function to stroke victims, and much more.

What Are Stem Cells?

Stem cells are undifferentiated cells than can produce (differentiate) cells of a specific or specialized type. Stem cells divide and produce new differentiated cells throughout your life. For example, as cell damage occurs (as in a cut), new skin cells are produced by stem cells to repair the cut.

Stem cells circulating in your blood can reach any organ that needs repair. The stem cells at that organ can produce exactly the kinds of cells needed to repair the organ so it functions normally again. The more stem cells in circulation, the faster the healing process occurs.

Everyone has stem cells. Because cells normally die off, stem cells are required for life. Some experts say we could live only a few hours if we had no stem cells.

Adult stem cells from your own body can be harvested from many sources. Most popular sources of stem cells are your bone marrow or your fat or adipose tissue through liposuction. The adipose tissue is processed in a way that separates the fat from the stem cells. The stem cells are them be injected in areas of the body that require repair.

Adult Stem Cell Therapy for Rheumatoid Arthritis and Osteoarthritis – Neil Riordan, PhD

Photo by handarmdoc

Dr. Riordan discusses focuses on mesenchymal stem cells harvested from fat tissue and the role they play in reducing inflammation, repairing tissue and modulating the immune system.

Stem Cells: Current Clinical Trials and Beyond

There are currently over 2,000 studies that are actively investigating stem cells or recruiting people to participate in a clinical trial involving stem cells. As of this writing, several of these studies are:

Results of stem cell trials have shown that injections have helped regrow cartilage, reducing or eliminating joint discomfort. Stem cells have helped restore corneas, repair heart damage, treat stroke victims, and even show promise in helping repair spinal cord injuries. Stem cells have helped diabetic patients restore circulation in their legs to avoid amputation.

As you can imagine, many studies are first done on animals to see if a certain treatment is effective. Those treatments that are effective can then be using in human trials.

One study, Stem cell therapy in a caprine model of osteoarthritis, investigating the usefulness of stem cells for regeneration of the medial meniscus or fibrocartilage in the joints of goats. Adult goat stem cells were introduced into the joints. The study noted “marked regeneration” of the meniscus. Repair tissue was noted after 6 weeks, and after 20 weeks further repair tissue was noted in 7 of 9 joints treated. The reseachers concluded that, “This study suggests that there may be a therapeutic benefit associated with intraarticular injection of stem cells following traumatic injury to the knee.”

Stem Cells: Results of Applications in Humans

Knee arthritis two years after stem cell therapy by Harry Adelson, N.D.

Carrie describes her outcome two years after stem cell therapy for her painful, arthritic knees by Harry Adelson, N.D.

Stem Cell Treatment For Knees: Mycal’s Story

Mycal was in constant pain which was impairing his function and quality of life. He wanted to avoid invasive knee replacement therapy. He chose adult stem cell therapy and watch him now tackle his game pain free! Stem Cell therapy for joint injuries are an ideal choice for those looking to avoid invasive surgery and prolonged downtime.

Enhance Your Stem Cells

You can receive stem cells in your joints or an intravenously for a whole body infusion in many clinics throughout the United States. Typically, the clinic will use fat cells taken, via liposuction, from your own body. The fat cells are placed in a centrifuge where the stem cells can be concentrated and extracted. The cells are then introduced into your body where they begin their work.

All this takes just a couple of hours. You’ll experience no “down time” and can go about your daily activities after the injections.

At this time, the cost of this procedure is approximately $4000 for one area ( for example, a knee or a shoulder) and $6000 for two areas (both knees or both shoulders). Insurance does not currently cover this procedure so you will have to pay for it yourself.

Stem Cell Enhancing Supplements

Because the cost such procedures more than many people can afford, some people are turning to supplements than can enhance stem cell production or mobilization. One such product is shown below. Investigate it and use it if you think it could help you.

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Stop Cancer Before it Starts

There are many organizations dedicated to finding the causes of and cures for cancer. You probably know recognize many of these such as:

  • The American Cancer Society
  • Cancer Research Institute
  • The Lance Armstrong Foundation
  • Lungevity Foundation
  • Susan G. Koman for the Cure
  • Leukaemia Research Fund

Yet, none of these organizations will be of much benefit to you if you do not practice good cancer prevention strategies.

Stop Cancer Before it Starts

Your probably already know how to prevent most cancers. We don’t need more research to discover these simple cancer stopping techniques.

tobacco photo

Photo by simone.brunozzi

  • Don’t smoke or use tobacco.
  • Eat healthy foods. This means plenty of fruits and vegetables, avoid processed meats and, if you must drink alcohol, drink in moderation.
  • Avoid obesity. Maintain a healthy weight and get plenty of exercise.
  • Avoid overexposure to the sun. Skin cancer is a common form of cancer.
  • Avoid carcinogens. These include viruses, bacteria, and parasites as well as air, water and soil pollution.
  • Avoid a compromised immune system.

Some Cancer Prevention Research to Keep in Mind

Eat Your Veggies

One study published in the journal Epidemiology studied how fruits and vegetables affected rates of cancer of the colon, rectum, and breast. The authors indicated that carotenoids, flavonoids, phenols, isothiocynates, fiber, and vitamins C and E could have anti-carcinogenic effects.

They found that raw carrots were the only vegetable that lowered cancer risks by 20% or more for all three types of cancer. They also found that apples, pears, and kiwi were associated with at least a 5% risk reduction for all three cancer types.

Overall high intake of raw vegetables lowered risks by 20% for colon cancer, 18% for cancer of the rectum, and 15% for breast cancer.

Cooked vegetables also reduced risks by 28% for colon cancer, 20% for cancer of the rectum, and 4% for breast cancer.

Watch Out for Sugar

Cancer cells love glucose (blood sugar). They take in and metabolize glucose faster than normal cells.
sugar photo
This fact allows positron emission tomography (PET) scans to detect cancerous tumors without invasive operations. This is possible by giving the patient a glucose analogue of slightly radioactive FDG, The cancer cells suck this up and it accumulates in cancerous tumors and can easily be detected in a PET scan.

Another study published in the journal Cancer investigated various glucose transport mechanisms in human breast cancer.

Glucose transport across cell boundaries is performed with the help of various protein enzymes. They found that the so-called Glut-1, Glut-2 and Glut-4 protein enzymes were active in breast cancer, but Glut-3 and Glut-5 mechanisms were not as active. Glut-1 was the most actives means of taking glucose into breast cancer cells. Such studies can help identify ways to slow down or inhibit the sugar feeding of cancer cells.

Another study published in the British Journal of Cancer looked at breast cancer rates in various countries. The researchers found that the rate of breast cancer in older women (aged 65-69) were positively correlated with sugar and fat consumption.

Yet another study published in The American Journal of Clinical Nutrition examined risks for pancreatic cancer and consumption of sugar sweetened foods. The study looked at 77,797 women and men.

This study found that those who consumed the most sugar were 1.95 times as likely to get pancreatic cancer as those consuming the least amount of sugar. Similarly for soft drinks, those who consumed most were 2.3 times as likely to get pancreatic cancer as those who consumed the fewest soft drinks.

The researchers thought that high levels of blood glucose created oxidative stress which resulted in free radical damage to the pancreatic cells. The idea is that the regions of the pancreas produce hormones have low concentrations of antioxidant enzymes. Thus, they are especially susceptible to glucose created free radicals.

Yet another study published in the British Medical Journal examined how the consumption of sugar and fat affected the risk of colorectal cancer.

They found that the overall calorie intake of those with large bowel cancer was 18% higher than their control group without cancer. Those with cancer consumed 21% more carbohydrates than those without cancer.

The cancer patients consumed 41% more sugars with little or no fiber and 19% less natural sugars with fiber. They found that the third of the study group consuming the most refined sugars (with high energy to fiber ratios) had an 8 times greater risk of contracting large bowel cancer than those in the lower third of refined sugar consumption.

If you’re not convinced already, another study published in the journal Cancer Causes and Control looked at the medical history of 98,030 women aged 55 to 69 years in Iowa. These women were mailed a questionnaire on known and suspected cancer risk-factors.

They found that BMI was related directly to cancer risk. Cancer risk for 60% of the women with the highest BMIs was from 40 to 70 percent higher than for those in the lowest 40% of BMIs. There was also double the risk of colon cancer in women consuming the most sucrose-containing foods.

You Can Stop Cancer Before it Starts

Research tells us not only the causes of cancer, but how to prevent many cancers types.

Cancer prevention strategies include consuming healthy fruits and vegetables and avoiding processed sugars that are depleted of fiber.

Unfortunately, this requires some effort on your part. You’ll need to about most of the manufactured foods that contain lots of added sugars. And, you’ll need to eat more raw fruits and vegetables.

If you like fruit or vegetable juices, switch to blended smoothies that retain the natural fiber.

Cancer prevention is a choice you must make. Make the right choices and stay healthy.