Metabolic syndrome is a group of symptoms that have been associated with an increased risk of type 2 diabetes and cardiovascular diseases. About 35% of the US adult population has metabolic syndrome. For those aged 60 or more, the rate is close to 50%.
Women are more likely to suffer with metabolic syndrome than men, and Hispanics have a higher rate than non-Hispanics.
Just What is Metabolic Syndrome?
Metabolic syndrome is a group of 5 symptoms. If you have 3 or more of these symptoms you are said to have metabolic syndrome. These symptoms are:
Elevated blood pressure of 130/85 or more.
High triglycerides of 150 mg/dl or more
Low HDL cholesterol, less than or equal to 40mg/dl for men and 50mg/dl in women
Elevated fasting blood glucose levels of 100 mg/dl or more
Central obesity generally associated with a BMI of 30 or more
A study reported in the the Journal of the American Medical Association (JAMA) reported that metabolic syndrome is increasing long term in the United States. In 2003-2004 the rate was 32.9% but increased to 34.7% in 2011-2012, a 5% increase. Some short term studies indicate that in recent years the rate have leveled out.
The prevalence of metabolic syndrome means that many people are suffering from increased risks for a number of diseases including heart disease, stroke and diabetes. And often the symptoms and diseases result in limitations of lifestyle options. In addition, a study of members of 3 health care plans indicated that those with 3 symptoms had 60% higher costs for health care than those without symptoms. And, the costs increased by a further 24% when a fourth or or fifth symptom was added.
These individual symptoms are pretty common among Americans. About a third of Americans have high blood pressure. About a third of American have high triglycerides. A fifth of American adults have low HDL cholesterol. Slightly under 10% of the population has elevated fasting blood glucose levels. And, a third of the population is obese.
Of the 15 initial volunteers, 12 completed the study. After 8 weeks, statistically significant reductions were noted in body mass index (BMI), body weight, fat content, lean body mass and basal metabolic rate.
On average, the volunteers went from 146 pounds to 141 pounds, a loss of 5 pounds. Average BMI decreased from 24.92 to 23.99. Body fat went from 65.3 pounds to 61.2 pounds.
This was a preliminary study of forskolin. Further double-blind placebo controlled studies were needed to confirm the effectiveness of forslolin for weight loss.
Fifteen randomly chosen men were assigned to take forskolin supplements (250 mg of 10% forskolin extract twice a day) for 12 weeks. The other 15 men were provided with a placebo. All of these men were overweight or obese with a BMI greater than 26 who were sedentary, non-active individuals who did not have asthma, low blood pressure or gastric ulcers.
The results shows that forskolin produced statistically significant changes.
The body fat percentage decreased for the forskolin group from 35.17% to 31.03%. The placebo group showed no significant difference in body fat percentage.
The fat mass of the forskolin group dropped a significant amount from 82.5 pounds to 72.5 pounds. The placebo group had no significant change is fat mass.
The researchers concluded that “forskolin promotes favorable changes in body composition by significantly decreasing percentage body fat and fat mass and increasing bone mass.” They believed that forskolin worked to activate free fatty acid release from the fat cells, making fat more available for the production of energy in the body–thus “burning” more fat.
Each member of the study took two capsules each day. Seven members received capsules containing 250 mg of 10% forskolin extract while 12 members received a similar placebo. They took one capsule in the morning and one in the evening a half hour before mealtime.
The results of this study did not show statistically significant differences between the forskolin group and the placebo group. But, it should be noted that the number of participants was smaller than the men’s study, so to be statistically significant any differences needed to be large.
The actual results of this study, though not “statistically significant”, are still important to note.
The average body weight for the forskolin group decreased from 192.2 pounds to 190.9 pounds while the average body weight for the placebo group increased from 189.8 pounds to 192.7 pounds.
The average fat mass for the forskolin group decreased slightly from 74.56 pounds to 74.1 pounds while the average fat mass for the placebo group increased from 68.93 pounds to 71.34 pounds.
These changes for the forskolin group are in a healthful direction, while the changes for the placebo group tended to be unhealthy. For most people, these results would be seen as a victory!
While this study did not show statistically significant results, the results point in the right direction.
Is Forskolin a Miracle Herb?
Dr. Oz calls forskolin “lightening in a bottle.” But, he exaggerates everything to make a point, and often to make a profit.
Cardiovascular disease: Forskolin has been shown to lower blood pressure by relaxing the vascular smooth muscles. It helps increase oxygen consumption and increases blood flow in the brain and could help in stroke recovery.
Asthma and allergies: Dry forskolin powder in aerosol form helps bronchodilation improving breathing.
Psoriasis: The ability of forskolin to regulate cAMP levels benefits sufferers of psoriasis.
Glaucoma and Increased Intraocular Pressure: Some studies have shown forskolin to reduce pressure inside the eye, or intraocular pressure of glaucoma.
Depresion: Animal studies show forskolin may act as an antidepressant.
Hypothyroidism: Forskolin has has shown to increase thyroid hormone production and stimulate thyroid hormone release.
Cancer: Forskolin has been shown to reduced tumor colonization (melanoma) in the lungs by 70%.
Weight Loss: Several studies in humans have shown that forskolin can induce weight loss or help prevent weight gain.
Digestion: Forskolin studies indicate it stimulate digestive secretions including hydrochloric acid, pepsin, amylase, and pancreatic enzymes.
Forskolin seems to have many positive effects on the human body, including weight loss.
For those struggling to lose weight, forskolin may be the answer.
Forskolin works to activate free fatty acid release from the fat cells so fat can be burned. You can burn fat even faster with 7 Keto DHEA which increases thermogenic activity within your body. This could be the combination that gives you success in your fat loss efforts.
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