Tag Archives: glucose

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Does Carbohydrate Restriction Fight Cancer? Use the Warburg Effect to Fight Cancer

Have we known that carbohydrate restriction fights cancer for nearly 100 years? One of the defining characteristics of cancer cells is the inefficient metabolism of glucose to lactate even in the presence of oxygen. This aerobic glycloysis (the breakdown of glucose by enzymes without oxygen) is known as the Warburg effect and has been known since the 1920s. Yet, little has been done to utilize this fact in helping to prevent or treat cancer.

The National Cancer Institute predicts that “in 2018, an estimated 1,735,350 new cases of cancer will be diagnosed in the United States and 609,640 people will die from the disease.”

In spite of all the cancer research, the number of people getting cancer in on the increase.

New Cancers in the United States

Shouldn’t we limit the primary nutrient of cancer cells as a means of fighting cancer?

Sugar is a Key Nutrient for Cancer Cells

Your body typically processes glucose (a sugar from carbohydrates) in two ways. Each way produces ATP molecules (adenosine 5′-triphosphate, the energy source for all cells of the body). Continue reading

Why Can’t I Lose Weight?

fat in gym photo

Photo by ~Twon~

You’ve gone to the gym to do aerobics. You’ve done crunches and tried hours of spinning classes. You’ve done resistance exercises to build muscle to raise your metabolism.

You’ve tried the Zone diet, the South Beach diet, the Mediterranean diet, and even the Weight Watchers diet.

And you’re still ready to shout: Why Can’t I Lose Weight?

Missing Key to Weight Loss

You probably know that to lose weight, especially to lose fat, you need to cut back on calories. Calories represent the energy value of foods. Now, the cells of your body get their energy from these sources: Continue reading

Stop Cancer Before it Starts

There are many organizations dedicated to finding the causes of and cures for cancer. You probably know recognize many of these such as:

  • The American Cancer Society
  • Cancer Research Institute
  • The Lance Armstrong Foundation
  • Lungevity Foundation
  • Susan G. Koman for the Cure
  • Leukaemia Research Fund

Yet, none of these organizations will be of much benefit to you if you do not practice good cancer prevention strategies.

Stop Cancer Before it Starts

Your probably already know how to prevent most cancers. We don’t need more research to discover these simple cancer stopping techniques.

tobacco photo

Photo by simone.brunozzi

  • Don’t smoke or use tobacco.
  • Eat healthy foods. This means plenty of fruits and vegetables, avoid processed meats and, if you must drink alcohol, drink in moderation.
  • Avoid obesity. Maintain a healthy weight and get plenty of exercise.
  • Avoid overexposure to the sun. Skin cancer is a common form of cancer.
  • Avoid carcinogens. These include viruses, bacteria, and parasites as well as air, water and soil pollution.
  • Avoid a compromised immune system.

Some Cancer Prevention Research to Keep in Mind

Eat Your Veggies

One study published in the journal Epidemiology studied how fruits and vegetables affected rates of cancer of the colon, rectum, and breast. The authors indicated that carotenoids, flavonoids, phenols, isothiocynates, fiber, and vitamins C and E could have anti-carcinogenic effects.

They found that raw carrots were the only vegetable that lowered cancer risks by 20% or more for all three types of cancer. They also found that apples, pears, and kiwi were associated with at least a 5% risk reduction for all three cancer types.

Overall high intake of raw vegetables lowered risks by 20% for colon cancer, 18% for cancer of the rectum, and 15% for breast cancer.

Cooked vegetables also reduced risks by 28% for colon cancer, 20% for cancer of the rectum, and 4% for breast cancer.

Watch Out for Sugar

Cancer cells love glucose (blood sugar). They take in and metabolize glucose faster than normal cells.
sugar photo
This fact allows positron emission tomography (PET) scans to detect cancerous tumors without invasive operations. This is possible by giving the patient a glucose analogue of slightly radioactive FDG, The cancer cells suck this up and it accumulates in cancerous tumors and can easily be detected in a PET scan.

Another study published in the journal Cancer investigated various glucose transport mechanisms in human breast cancer.

Glucose transport across cell boundaries is performed with the help of various protein enzymes. They found that the so-called Glut-1, Glut-2 and Glut-4 protein enzymes were active in breast cancer, but Glut-3 and Glut-5 mechanisms were not as active. Glut-1 was the most actives means of taking glucose into breast cancer cells. Such studies can help identify ways to slow down or inhibit the sugar feeding of cancer cells.

Another study published in the British Journal of Cancer looked at breast cancer rates in various countries. The researchers found that the rate of breast cancer in older women (aged 65-69) were positively correlated with sugar and fat consumption.

Yet another study published in The American Journal of Clinical Nutrition examined risks for pancreatic cancer and consumption of sugar sweetened foods. The study looked at 77,797 women and men.

This study found that those who consumed the most sugar were 1.95 times as likely to get pancreatic cancer as those consuming the least amount of sugar. Similarly for soft drinks, those who consumed most were 2.3 times as likely to get pancreatic cancer as those who consumed the fewest soft drinks.

The researchers thought that high levels of blood glucose created oxidative stress which resulted in free radical damage to the pancreatic cells. The idea is that the regions of the pancreas produce hormones have low concentrations of antioxidant enzymes. Thus, they are especially susceptible to glucose created free radicals.

Yet another study published in the British Medical Journal examined how the consumption of sugar and fat affected the risk of colorectal cancer.

They found that the overall calorie intake of those with large bowel cancer was 18% higher than their control group without cancer. Those with cancer consumed 21% more carbohydrates than those without cancer.

The cancer patients consumed 41% more sugars with little or no fiber and 19% less natural sugars with fiber. They found that the third of the study group consuming the most refined sugars (with high energy to fiber ratios) had an 8 times greater risk of contracting large bowel cancer than those in the lower third of refined sugar consumption.

If you’re not convinced already, another study published in the journal Cancer Causes and Control looked at the medical history of 98,030 women aged 55 to 69 years in Iowa. These women were mailed a questionnaire on known and suspected cancer risk-factors.

They found that BMI was related directly to cancer risk. Cancer risk for 60% of the women with the highest BMIs was from 40 to 70 percent higher than for those in the lowest 40% of BMIs. There was also double the risk of colon cancer in women consuming the most sucrose-containing foods.

You Can Stop Cancer Before it Starts

Research tells us not only the causes of cancer, but how to prevent many cancers types.

Cancer prevention strategies include consuming healthy fruits and vegetables and avoiding processed sugars that are depleted of fiber.

Unfortunately, this requires some effort on your part. You’ll need to about most of the manufactured foods that contain lots of added sugars. And, you’ll need to eat more raw fruits and vegetables.

If you like fruit or vegetable juices, switch to blended smoothies that retain the natural fiber.

Cancer prevention is a choice you must make. Make the right choices and stay healthy.

Diabulimia: The World’s Most Dangerous Eating Disorder

Diabulimia is the combination of type 1 diabetes with the eating disorder bulimia.

People with type 1 diabetes have a defective pancreas that does not make insulin. And insulin is needed for glucose to enter the body’s cells for energy or storage.

bulimia photo

Photo by olgaberrios

People with bulimia are overly concerned about their weight. They often eat to excess and then cause themselves to purge, usually by vomiting or taking laxatives, but some exercise to an excessive degree.

Combine these physical and psychological illnesses and you have a person that recognizes that by reducing or withholding insulin he or she can prevent their body from utilizing the glucose in the blood. Glucose cannot be used for energy or be converted and stored for future use as fat. This causes their body to use stored fat and protein for energy. In other words, insulin helps build more fat. Withholding insulin is a way of eating whatever you want but still losing weight.

Not getting enough insulin causes blood sugar levels to rise. A condition of high blood glucose levels is called hyperglycemia. Excess sugar (glucose) is secreted in the urine. Calories are in this way purged from the body.

Hyperglycemia is a dangerous condition that can result in permanent damage to the body. High glucose levels cause damage to small blood vessels and nerves. The damaged blood vessels affect organs such as the eye, heart, and kidneys. Nerve damage results in weakness, tingling, pain, and numbness in the feet and hands.

These conditions can worsen over time. Sight can deteriorate and become blurred or blindness can result. Heart disease and stroke are common in patients with diabetes. Kidneys can fail and require dialysis. Foot ulcers can become so bad a patient has to use a wheelchair and eventually amputation may be required.

The Dangers of Diabulimia

Gemma, Nabeelah and Becky are some of thousands of people who suffer from Diabulimia. Usual eating disorder treatment does not work, but medical experts hope to change that.

If you have been affected by the issues raised in this documentary, the these organizations within the UK may be able to help.
Video Rating: / 5

The American Diabetes Association tells us that “girls and women with type 1 diabetes are twice as likely to develop an eating disorder as those without diabetes?” It’s not surprising that the death rate of those with type 1 diabetes is three times higher when an eating disorder is present.

My Diabetes Journey” JDRF video contest entry. A story of dance, Type 1 diabetes, eating disorders, diabulimia, and RECOVERY!

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